Publication: Advanced 3Y-TZP bioceramic doped with Al2O3 and CeO2 potentially for biomedical implant applications
Date
2019
Authors
Golieskardi M.
Satgunam M.
Ragurajan D.
Hoque M.E.
Ng A.M.H.
Shanmuganantha L.
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor and Francis Ltd.
Abstract
This research studies 3�mol% yttria-stabilized zirconia (3Y-TZP) investigating the effects of Al2O3 and CeO2 dopants on the stability of tetragonal phase and the microstructure of 3Y-TZP determined over the operating temperature ranging from 1250�C to 1550�C. It is found that the mechanical properties of 3Y-TZP are dependent on the sintering temperature and the dopant amount. The current study reveals that the optimum sintering temperature is 1450�C for all 3Y-TZP samples while attaining more than 98% of the theoretical density (6.1g/cm3). With optimum dopants, the 3Y-TZP ceramic samples demonstrate the Vickers hardness of 10.9 GPa and fracture toughness (KIC) of 10 MPa.m1/2. Fracture toughness increases with the dopant content, indicating that the annihilation of oxygen vacancies in 3Y-TZP is responsible for the instability of the t-ZrO2 lattice. To investigate the biocompatibility of 3Y-TZP, cell culture study was performed using osteoblast cells. The results demonstrate a high percentage of cell attachment and proliferation that confirmed the biocompatibility of synthesized 3Y-TZP. � 2019, � 2019 Informa UK Limited, trading as Taylor & Francis Group.
Description
Alumina; Aluminum oxide; Bioceramics; Biocompatibility; Biomechanics; Cell culture; Cell proliferation; Cells; Cerium oxide; Cytotoxicity; Mechanical properties; Morphology; Sintering; Vickers hardness; Yttria stabilized zirconia; Yttrium oxide; Zirconia; 3Y-TZP; Biomedical implant applications; Cell morphology; Operating temperature; Osteoblast cells; Sintering temperatures; Theoretical density; Yttria-stabilized zirconia (3Y-TZP); Fracture toughness