Publication:
Development of hydrophobic reduced graphene oxide as a new efficient approach for photochemotherapy

dc.citedby31
dc.contributor.authorMousavi S.M.en_US
dc.contributor.authorLow F.W.en_US
dc.contributor.authorHashemi S.A.en_US
dc.contributor.authorSamsudin N.A.en_US
dc.contributor.authorShakeri M.en_US
dc.contributor.authorYusoff Y.en_US
dc.contributor.authorRahsepar M.en_US
dc.contributor.authorLai C.W.en_US
dc.contributor.authorBabapoor A.en_US
dc.contributor.authorSoroshnia S.en_US
dc.contributor.authorGoh S.M.en_US
dc.contributor.authorTiong S.K.en_US
dc.contributor.authorAmin N.en_US
dc.contributor.authorid57217768274en_US
dc.contributor.authorid56513524700en_US
dc.contributor.authorid57201310181en_US
dc.contributor.authorid57190525429en_US
dc.contributor.authorid55433849200en_US
dc.contributor.authorid57206844407en_US
dc.contributor.authorid23767603500en_US
dc.contributor.authorid54879860000en_US
dc.contributor.authorid36501392200en_US
dc.contributor.authorid57208784235en_US
dc.contributor.authorid25521891600en_US
dc.contributor.authorid15128307800en_US
dc.contributor.authorid7102424614en_US
dc.date.accessioned2023-05-29T08:10:35Z
dc.date.available2023-05-29T08:10:35Z
dc.date.issued2020
dc.descriptionBiocompatibility; Biomedical engineering; Cell death; Chemotherapy; Disintegration; Infrared devices; Reduced Graphene Oxide; Absence of cells; Clinical settings; Medical technologies; Membrane disruption; Near infrared region; Phosphatidylserine; Photochemotherapy; Reduced graphene oxides (RGO); Grapheneen_US
dc.description.abstractNowadays, chemotherapy is one of the crucial and common therapies in the world. So far, it has been revealed to be highly promising, yet patients suffer from the consequences of severe negative medical dosages. In order to overcome these issues, the enhancement of photothermal chemotherapy with reduced graphene oxide (rGO) as a photothermal agent (PTA) is widely utilised in current medical technologies. This is due to its high near-infrared region (NIR) response, in vitro or in vivo organism biocompatibility, low risk of side effects, and effective positive results. Moreover, rGO not only has the ability to ensure that selective cancer cells have a higher mortality rate but can also improve the growth rate of recovering tissues that are untouched by necrosis and apoptosis. These two pathways are specific diverse modalities of cell death that are distinguished by cell membrane disruption and deoxyribonucleic acid (DNA) disintegration of the membrane via phosphatidylserine exposure in the absence of cell membrane damage. Therefore, this review aimed to demonstrate the recent achievements in the modification of rGO nanoparticles as a PTA as well as present a new approach for performing photochemotherapy in the clinical setting. � 2020 The Royal Society of Chemistry.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1039/d0ra00186d
dc.identifier.epage12863
dc.identifier.issue22
dc.identifier.scopus2-s2.0-85083376546
dc.identifier.spage12851
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85083376546&doi=10.1039%2fd0ra00186d&partnerID=40&md5=91b2426effe695dbe9e00879e0fedfc8
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/25535
dc.identifier.volume10
dc.publisherRoyal Society of Chemistryen_US
dc.relation.ispartofAll Open Access, Gold
dc.sourceScopus
dc.sourcetitleRSC Advances
dc.titleDevelopment of hydrophobic reduced graphene oxide as a new efficient approach for photochemotherapyen_US
dc.typeReviewen_US
dspace.entity.typePublication
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