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The occurrence of non-steroidal anti-inflammatory drugs (NSAIDs) in Malaysian urban domestic wastewater

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dc.citedby7
dc.contributor.authorMohd Hanafiah Z.en_US
dc.contributor.authorWan Mohtar W.H.M.en_US
dc.contributor.authorAbd Manan T.S.B.en_US
dc.contributor.authorBachi' N.A.en_US
dc.contributor.authorAbdullah N.A.en_US
dc.contributor.authorAbd Hamid H.H.en_US
dc.contributor.authorBeddu S.en_US
dc.contributor.authorMohd Kamal N.L.en_US
dc.contributor.authorAhmad A.en_US
dc.contributor.authorWan Rasdi N.en_US
dc.contributor.authorid57211619771en_US
dc.contributor.authorid25637975300en_US
dc.contributor.authorid57219650719en_US
dc.contributor.authorid57254417800en_US
dc.contributor.authorid57254179800en_US
dc.contributor.authorid57194976523en_US
dc.contributor.authorid55812080500en_US
dc.contributor.authorid56239107300en_US
dc.contributor.authorid6506760282en_US
dc.contributor.authorid56446926400en_US
dc.date.accessioned2023-05-29T09:42:27Z
dc.date.available2023-05-29T09:42:27Z
dc.date.issued2022
dc.descriptionCatchments; Dimers; Drug products; Ecology; Extraction; Mass spectrometry; Phase separation; Risk assessment; Sewage treatment plants; Wastewater treatment; Ecological risk assessment; Emerging contaminant; Gas chromatography mass spectrometry; Gaschromatography-mass spectrometry; Non-steroidal anti-inflammatory drug; Non-steroidal anti-inflammatory drugs; Sewage treatment plant; Sewage-treatment plants; Solid phase extraction; Solid-phase extraction; Gas chromatography; diclofenac; dimer; ibuprofen; ketoprofen; microplastic; monomer; naproxen; nonsteroid antiinflammatory agent; sorbent; surface water; drug; nonsteroid antiinflammatory agent; concentration (composition); drug; extraction method; risk assessment; wastewater; wastewater treatment; Article; calibration; catchment area (hydrology); comparative study; limit of detection; limit of quantitation; Malaysia; mass fragmentography; quality control; risk assessment; sewage treatment plant; solid phase extraction; urban area; waste water management; water quality; water sampling; wastewater; water pollutant; Malaysia; Indicator indicator; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Naproxen; Pharmaceutical Preparations; Waste Water; Water Pollutants, Chemicalen_US
dc.description.abstractThe water stream has been reported to contain non-steroidal anti-inflammatory drugs (NSAIDs), released from households and premises through discharge from Sewage Treatment Plant (STP). This research identifies commonly consumed NSAIDs namely ibuprofen (IBU), diclofenac (DIC), ketoprofen (KET) and naproxen (NAP) in the influent wastewater from two urban catchments (i.e. 2 STPs). We expand our focus to assess the efficiency of monomer (C18) and dimer (HLB) types of sorbents in the solid phase extraction method followed by gas chromatography mass spectrometry (GCMS) analysis and optimize model prediction of NSAIDs in the influent wastewater using I-Optimal design. The ecological risk assessment of the NSAIDs was evaluated. The HLB produced reliable analysis for all NSAIDs under study (STP1: 6.7 � 10?3 mg L?1 to 2.21 � 10?1 mg L?1, STP2: 1.40 � 10?4 mg L?1 to 9.72 � 10?2 mg L?1). The C18 however, selective to NAP. Based on the Pearson proximity matrices, the DICHLB can be a good indicator for IBUHLB (0.565), NAPC18 (0.721), NAPHLB (0.566), and KETHLB (0.747). The optimized model prediction for KET and NAP based on DIC are successfully validated. The risk quotients (RQ) values of NSAIDs were classified as high (RQ > 1), medium (RQ, 0.1�1) and low (RQ, 0.01�0.1) risks. The optimized models are beneficial for major NSAIDs (KET and NAP) monitoring in the influent wastewater of urban domestic area. An upgrade on the existing wastewater treatment infrastructure is recommended to counteract current water security situation. � 2021 Elsevier Ltden_US
dc.description.natureFinalen_US
dc.identifier.ArtNo132134
dc.identifier.doi10.1016/j.chemosphere.2021.132134
dc.identifier.scopus2-s2.0-85114688683
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85114688683&doi=10.1016%2fj.chemosphere.2021.132134&partnerID=40&md5=85371441b0d6debbcad8b9c22962e85b
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/27306
dc.identifier.volume287
dc.publisherElsevier Ltden_US
dc.sourceScopus
dc.sourcetitleChemosphere
dc.titleThe occurrence of non-steroidal anti-inflammatory drugs (NSAIDs) in Malaysian urban domestic wastewateren_US
dc.typeArticleen_US
dspace.entity.typePublication
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