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Blood glucose and sepsis score on sepsis patients requiring insulin therapy

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dc.contributor.authorMohamad Suhaimi F.en_US
dc.contributor.authorJamaludin U.K.en_US
dc.contributor.authorAbdul Razak N.N.en_US
dc.contributor.authorPretty C.G.en_US
dc.contributor.authorMd. Ralib A.en_US
dc.contributor.authorMat Nor M.B.en_US
dc.contributor.authorDzaharudin F.en_US
dc.contributor.authorid36247893200en_US
dc.contributor.authorid55330889600en_US
dc.contributor.authorid37059587300en_US
dc.contributor.authorid6508290605en_US
dc.contributor.authorid37031770900en_US
dc.contributor.authorid57226799207en_US
dc.contributor.authorid35219916100en_US
dc.date.accessioned2023-05-29T06:57:11Z
dc.date.available2023-05-29T06:57:11Z
dc.date.issued2018
dc.descriptionBiomedical engineering; Blood; Diagnosis; Glucose; Insulin; Blood glucose; Blood glucose level; Clinical guideline; Insulin sensitivity; Insulin therapy; Patient condition; Provide guidances; Sepsis; Patient treatmenten_US
dc.description.abstractEarly treatment of sepsis is crucial in improving the patient condition and reduces mortality. The lack of information and methods to diagnose sepsis at an early stage is a significant barrier to early treatment. Treatment is normally based on clinical judgment since blood cultures are negative in the majority of sepsis or septic shock cases as reported in several studies. Even with blood cultures result, a delay in diagnosis may happen while waiting for the results. Therefore, clinical guidelines are still required to provide guidance for the clinician caring for a patient with severe sepsis or septic shock. In this study, a validated glucose-insulin model is used to capture patient-specific insulin sensitivity profile. The validated model is incorporated with a sepsis system to create a glucose-insulin model that describe sepsis occurrence. The relationship between insulin sensitivity, blood glucose and sepsis score is investigated using a retrospective data of 8 patients admitted in the Tengku Ampuan Afzan Hospital, Kuantan. Results indicate that there was a significant relationship between blood glucose level and sepsis score (p�<�0.001), and insulin sensitivity with a sepsis score (p�<�0.001). Additionally, blood glucose level was higher in a severe sepsis group compared to the non-sepsis group. Whereas, insulin sensitivity is lower in a severe sepsis group. Insulin sensitivity profile can be incorporated with the sepsis system for monitoring sepsis patients requiring insulin therapy as seen in this study. Thus, the sepsis glucose-insulin model can potentially be used as an indicator or tools for sepsis diagnosis. � 2018, Springer Science+Business Media Singapore.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1007/978-981-10-7554-4_46
dc.identifier.epage269
dc.identifier.scopus2-s2.0-85038128429
dc.identifier.spage265
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85038128429&doi=10.1007%2f978-981-10-7554-4_46&partnerID=40&md5=93dc32c3a5d2e1fbf709d67e7ec27776
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/24227
dc.identifier.volume67
dc.publisherSpringer Verlagen_US
dc.sourceScopus
dc.sourcetitleIFMBE Proceedings
dc.titleBlood glucose and sepsis score on sepsis patients requiring insulin therapyen_US
dc.typeConference Paperen_US
dspace.entity.typePublication
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