Publication:
Estimation of plasma insulin and endogenous insulin secretion in critically III patients using intensive control insulin-nutrition-glucose model

dc.contributor.authorJamaludin U.K.en_US
dc.contributor.authorSuhaimi F.M.en_US
dc.contributor.authorRazak N.N.A.en_US
dc.contributor.authorRalib A.M.en_US
dc.contributor.authorNor M.B.M.en_US
dc.contributor.authorid55330889600en_US
dc.contributor.authorid36247893200en_US
dc.contributor.authorid37059587300en_US
dc.contributor.authorid37031770900en_US
dc.contributor.authorid57226799207en_US
dc.date.accessioned2023-05-29T06:40:23Z
dc.date.available2023-05-29T06:40:23Z
dc.date.issued2017
dc.description.abstractThe objective of this study is to estimate total plasma insulin level and endogenous insulin secretion by using Intensive Control Insulin-Nutrition-Glucose (ICING) model and 90 critically ill patients� data from Hospital Tengku Ampuan Afzan, Kuantan. Integral-based method was applied to solve mathematical equations defined in ICING model to find critical parameters of insulin sensitivity (SI) and results of total endogenous insulin secretion and total plasma insulin level were presented in median and 95% confidence interval (CI). It is reported that the total median plasma insulin is 1.35�106 mU while (6.59�105, 2.79�106) mU is in 95% CI, and the total median endogenous insulin secretion is 12.9% from the total median plasma insulin. The results elucidated the effectiveness of current practice via Intensive Insulin Infusion Therapy (IIT) and also suggest a further study on investigating the incretin mechanism which is strongly believed to contribute to the total plasma insulin level and help to simulate endogenous insulin secretion. � 2017 American Scientific Publishers All rights reserved.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1166/asl.2017.7410
dc.identifier.epage5514
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85027880849
dc.identifier.spage5511
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85027880849&doi=10.1166%2fasl.2017.7410&partnerID=40&md5=2dce9c146c6090d6b188be6660019e01
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/23425
dc.identifier.volume23
dc.publisherAmerican Scientific Publishersen_US
dc.relation.ispartofAll Open Access, Green
dc.sourceScopus
dc.sourcetitleAdvanced Science Letters
dc.titleEstimation of plasma insulin and endogenous insulin secretion in critically III patients using intensive control insulin-nutrition-glucose modelen_US
dc.typeArticleen_US
dspace.entity.typePublication
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