Publication:
Propolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulations

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dc.citedby2
dc.contributor.authorGhosh S.en_US
dc.contributor.authorAl-Sharify Z.T.en_US
dc.contributor.authorMaleka M.F.en_US
dc.contributor.authorOnyeaka H.en_US
dc.contributor.authorMaleke M.en_US
dc.contributor.authorMaolloum A.en_US
dc.contributor.authorGodoy L.en_US
dc.contributor.authorMeskini M.en_US
dc.contributor.authorRami M.R.en_US
dc.contributor.authorAhmadi S.en_US
dc.contributor.authorAl-Najjar S.Z.en_US
dc.contributor.authorAl-Sharify N.T.en_US
dc.contributor.authorAhmed S.M.en_US
dc.contributor.authorDehghani M.H.en_US
dc.contributor.authorid57192654713en_US
dc.contributor.authorid57204908487en_US
dc.contributor.authorid55654685900en_US
dc.contributor.authorid6506961237en_US
dc.contributor.authorid56466035200en_US
dc.contributor.authorid57786611400en_US
dc.contributor.authorid57224821418en_US
dc.contributor.authorid57202514280en_US
dc.contributor.authorid57212216439en_US
dc.contributor.authorid57710506700en_US
dc.contributor.authorid57218553613en_US
dc.contributor.authorid57205364615en_US
dc.contributor.authorid57696704100en_US
dc.contributor.authorid57192214256en_US
dc.date.accessioned2023-05-29T09:36:53Z
dc.date.available2023-05-29T09:36:53Z
dc.date.issued2022
dc.descriptionantimicrobial activity; bee; COVID-19; literature review; mortality; severe acute respiratory syndrome; simulation; vaccine; virus; antiinflammatory agent; antivirus agent; biological product; propolis; drug therapy; human; Anti-Inflammatory Agents; Antiviral Agents; Biological Products; COVID-19; COVID-19 Vaccines; Humans; Propolis; SARS-CoV-2en_US
dc.description.abstractThis current study review provides a brief review of a natural bee product known as propolis and its relevance toward combating SARS-CoV viruses. Propolis has been utilized in medicinal products for centuries due to its excellent biological properties. These include anti-oxidant, immunomodulatory, anti-inflammatory, anti-viral, anti-fungal, and bactericidal activities. Furthermore, studies on molecular simulations show that flavonoids in propolis may reduce viral replication. While further research is needed to validate this theory, it has been observed that COVID-19 patients receiving propolis show earlier viral clearance, enhanced symptom recovery, quicker discharge from hospitals, and a reduced mortality rate relative to other patients. As a result, it appears that propolis could probably be useful in the treatment of SARS-CoV-2-infected patients. Therefore, this review sought to explore the natural properties of propolis and further evaluated past studies that investigated propolis as an alternative product for the treatment of COVID-19 symptoms. In addition, the review also highlights the possible mode of propolis action as well as molecular simulations of propolis compounds that may interact with the SARS-CoV-2 virus. The activity of propolis compounds in decreasing the impact of COVID-19-related comorbidities, the possible roles of such compounds as COVID-19 vaccine adjuvants, and the use of nutraceuticals in COVID-19 treatment, instead of pharmaceuticals, has also been discussed. � 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1007/s11356-022-21652-6
dc.identifier.epage58647
dc.identifier.issue39
dc.identifier.scopus2-s2.0-85133616080
dc.identifier.spage58628
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85133616080&doi=10.1007%2fs11356-022-21652-6&partnerID=40&md5=cd1a95335a8c42f891c58f1108046182
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/26811
dc.identifier.volume29
dc.publisherSpringer Science and Business Media Deutschland GmbHen_US
dc.relation.ispartofAll Open Access, Bronze, Green
dc.sourceScopus
dc.sourcetitleEnvironmental Science and Pollution Research
dc.titlePropolis efficacy on SARS-COV viruses: a review on antimicrobial activities and molecular simulationsen_US
dc.typeReviewen_US
dspace.entity.typePublication
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