Publication: Biomaterials for Bone Tissue Engineering: Properties and Applications
Date
2021
Authors
Zaroog O.S.
Satgunam M.
Wei L.C.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Tissue engineering is one of few emerging fields that focus solely on developing alternative treatment for tissue and organ repair. It is a multidisciplinary field that uses a combination of cells, engineering materials and suitable biochemical factors to enhance or replace biological function to produce a better clinical procedure to repair damaged tissues and organs. Biomaterials are incredibly significant in tissue engineering in various ways such as; acting as a substrate so that cell populations can attach and migrate, as a cell delivery vehicle, 3-D implant with a combination of specific cell types, to activate specific cellular function in the localized region as a drug carrier, to define the shape of regenerating tissue as a mechanical structure, and to provide space as a barrier membrane for tissue regeneration along with prevention of fibroblast ingrowth into the space. Hence with all the facts in mind, this paper is to do a thorough study and review on the specific research on the biomaterial�s applications and properties for bone tissue engineering which hopefully could discover a more suitable and affordable biomaterial which can substitutes and represent the future of new therapeutic approaches specifically aimed at clinical applications. � 2021 Elsevier Ltd. All rights reserved.