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Optimization of Metal Ion/Fuel Ratio for an Effective Combustion of Monticellite and Investigation of Its Microbial and Hemolytic Activity for Biomedical Applications

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dc.citedby1
dc.contributor.authorVijayakumar N.en_US
dc.contributor.authorVenkatraman S.K.en_US
dc.contributor.authorNandakumar R.en_US
dc.contributor.authorAlex R.A.en_US
dc.contributor.authorAbraham J.en_US
dc.contributor.authorMohammadi H.en_US
dc.contributor.authorEbadi M.en_US
dc.contributor.authorSwamiappan S.en_US
dc.contributor.authorid57337231200en_US
dc.contributor.authorid57191256805en_US
dc.contributor.authorid58665005900en_US
dc.contributor.authorid57290236600en_US
dc.contributor.authorid37048698100en_US
dc.contributor.authorid55573732500en_US
dc.contributor.authorid57204197808en_US
dc.contributor.authorid13410276900en_US
dc.date.accessioned2024-10-14T03:17:31Z
dc.date.available2024-10-14T03:17:31Z
dc.date.issued2023
dc.description.abstractBioactive silicates have gained popularity as bone graft substitutes in recent years due to their exceptional ability to bind to host tissues. The current study investigates the effect of changing the metal ion-to-fuel ratio on the properties and biological activity of monticellite prepared via the sol-gel connived combustion technique. Single-phasic monticellite was obtained at 900 �C, without any secondary-phase contaminants for the fuel-lean, stoichiometric, and fuel-rich conditions. SEM and TEM micrographs revealed the porous, spongy morphology of the materials. Because of the reduced crystallite size and higher surface area, the biomineralization of monticellite prepared under fuel-lean conditions resulted in more apatite deposition than those of the other two samples. The results show that the material has a good compressive strength comparable to natural bone, while its brittleness is equivalent to the lower moduli of bone. In terms of antibacterial and antifungal activities, the monticellite bioceramics outperformed the clinical pathogens. It can be used for bone tissue engineering and other biological applications due to its excellent anti-inflammatory and hemolysis inhibitory properties. � 2023 The Authors. Published by American Chemical Society.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1021/acsomega.3c03984
dc.identifier.epage36932
dc.identifier.issue40
dc.identifier.scopus2-s2.0-85174908908
dc.identifier.spage36919
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85174908908&doi=10.1021%2facsomega.3c03984&partnerID=40&md5=fe89b427fdbcc577d4e123d7d9e0fee3
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/33960
dc.identifier.volume8
dc.pagecount13
dc.publisherAmerican Chemical Societyen_US
dc.relation.ispartofAll Open Access
dc.relation.ispartofGold Open Access
dc.relation.ispartofGreen Open Access
dc.sourceScopus
dc.sourcetitleACS Omega
dc.titleOptimization of Metal Ion/Fuel Ratio for an Effective Combustion of Monticellite and Investigation of Its Microbial and Hemolytic Activity for Biomedical Applicationsen_US
dc.typeArticleen_US
dspace.entity.typePublication
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