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Development of graphene based nanocomposites towards medical and biological applications

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dc.citedby21
dc.contributor.authorMousavi S.M.en_US
dc.contributor.authorLow F.W.en_US
dc.contributor.authorHashemi S.A.en_US
dc.contributor.authorLai C.W.en_US
dc.contributor.authorGhasemi Y.en_US
dc.contributor.authorSoroshnia S.en_US
dc.contributor.authorSavardashtaki A.en_US
dc.contributor.authorBabapoor A.en_US
dc.contributor.authorPynadathu Rumjit N.en_US
dc.contributor.authorGoh S.M.en_US
dc.contributor.authorAmin N.en_US
dc.contributor.authorTiong S.K.en_US
dc.contributor.authorid57217768274en_US
dc.contributor.authorid56513524700en_US
dc.contributor.authorid57201310181en_US
dc.contributor.authorid54879860000en_US
dc.contributor.authorid6506711864en_US
dc.contributor.authorid57208784235en_US
dc.contributor.authorid57057868900en_US
dc.contributor.authorid36501392200en_US
dc.contributor.authorid57191580733en_US
dc.contributor.authorid25521891600en_US
dc.contributor.authorid7102424614en_US
dc.contributor.authorid15128307800en_US
dc.date.accessioned2023-05-29T08:12:31Z
dc.date.available2023-05-29T08:12:31Z
dc.date.issued2020
dc.descriptionBiocompatibility; Chemical vapor deposition; Controlled drug delivery; Nanocomposites; Quality control; Targeted drug delivery; Biological applications; Camptothecin (CPT); Chemical vapour deposition; Cytotoxic effects; Drug delivery applications; Functionalisation; Graphene nanocomposites; High specific surface area; Graphene; antiinfective agent; camptothecin; doxorubicin; firtecan; graphene; graphene oxide; nanocomposite; polymer; graphite; nanocomposite; biocompatibility; bioimaging; chemexfoliation; chemical procedures; chemical vapor deposition; cytotoxicity; diagnosis; drug delivery system; epitaxy; HCT 116 cell line; human; imaging; in vitro study; nonhuman; reduction (chemistry); regenerative medicine; Review; synthesis; tissue engineering; animal; chemistry; nanomedicine; procedures; Animals; Graphite; Humans; Nanocomposites; Nanomedicineen_US
dc.description.abstractGraphene and its derivative materials present high potential towards medical and biological applications, including drug delivery and bioimaging, due to their exceptional properties such as thermal conductivity and high specific surface area. The main focus of this work is to review the current development of graphene materials and the derivatives for biocompatible, bioimaging and drug delivery applications. Also, the synthesis methods with variation of graphene nanocomposites and the functionalisation will be further explained. For the graphene approaches, chemical vapour deposition (CVD) is the best-known technique to make high-quality graphene sheet by growth route with mass production. By considering the organic graphene nanocomposites, the biocompatibility and cytotoxic effects against graphene nanocomposites were evaluated for biomedical employments such as high quality bioimaging and effective drug delivery for cancer treatments. For example, graphene oxide incorporated with PEG and loaded with SN 38 for camptothecin analolgue as anticancer drug and revealed high cytotoxicity has an effect of 1000 times better effect than CPT in HCT-116 cells. Their drug delivery ability for both in-vivo and in-vitro applications compared to the controlled drugs such as doxorubicin (DOX) will be discussed accordingly. The graphene and its deriavatives possess some intriguing properties, which will lead to drug delivery due to strong biocompatibility and cyctotoxic effect towards biomedicine applications. � 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1080/21691401.2020.1817052
dc.identifier.epage1205
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85091054171
dc.identifier.spage1189
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85091054171&doi=10.1080%2f21691401.2020.1817052&partnerID=40&md5=c4fa4ad5cefbfebf705b4215a1e536db
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/25671
dc.identifier.volume48
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofAll Open Access, Gold
dc.sourceScopus
dc.sourcetitleArtificial Cells, Nanomedicine and Biotechnology
dc.titleDevelopment of graphene based nanocomposites towards medical and biological applicationsen_US
dc.typeReviewen_US
dspace.entity.typePublication
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