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A Fractional Perspective on the Dynamics of HIV, Considering the Interaction of Viruses and Immune System with the Effect of Antiretroviral Therapy

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dc.citedby8
dc.contributor.authorTang T.-Q.en_US
dc.contributor.authorJan R.en_US
dc.contributor.authorAhmad H.en_US
dc.contributor.authorShah Z.en_US
dc.contributor.authorVrinceanu N.en_US
dc.contributor.authorRacheriu M.en_US
dc.contributor.authorid57191995128en_US
dc.contributor.authorid57205596279en_US
dc.contributor.authorid58525153300en_US
dc.contributor.authorid57194441902en_US
dc.contributor.authorid26434973300en_US
dc.contributor.authorid57201688417en_US
dc.date.accessioned2024-10-14T03:17:27Z
dc.date.available2024-10-14T03:17:27Z
dc.date.issued2023
dc.description.abstractHIV infection is a worldwide health threat, necessitating a multifaceted strategy that includes prevention, testing, treatment and care. Moreover, it is essential to address the structural and social factors that influence the spread of this viral infection. In this study, we utilize fractional calculus to clarify the dynamics of HIV infection in vivo, specifically examining the interface amid the HIV and the immune system and taking into account the impact of antiretroviral therapy. We use important results from fractional theory to analyze our proposed model of HIV infection and developed a numerical scheme to depict the system�s dynamic behavior. By varying input factors, we were able to observe the system�s chaotic nature and track its trajectory, as well as examine the effect of viruses on T-cells. Our results reveal key factors affecting the system, and demonstrate the consequence of antiretroviral therapy on our proposed model of HIV. Moreover, we observe that the system�s strong non-linearity is responsible for the oscillation phenomena and identify the most sensitive parameters of the system. � 2023, The Author(s).en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1007/s44198-023-00133-5
dc.identifier.epage1344
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85166922342
dc.identifier.spage1327
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85166922342&doi=10.1007%2fs44198-023-00133-5&partnerID=40&md5=3691327d9e73894545ff8c0077e9cad3
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/33927
dc.identifier.volume30
dc.pagecount17
dc.publisherInstitute for Ionicsen_US
dc.relation.ispartofAll Open Access
dc.relation.ispartofHybrid Gold Open Access
dc.sourceScopus
dc.sourcetitleJournal of Nonlinear Mathematical Physics
dc.subjectAntiretroviral therapy
dc.subjectDynamical behavior
dc.subjectFractional-calculus
dc.subjectHIV dynamics
dc.subjectImmune system
dc.subjectNumerical scheme
dc.titleA Fractional Perspective on the Dynamics of HIV, Considering the Interaction of Viruses and Immune System with the Effect of Antiretroviral Therapyen_US
dc.typeArticleen_US
dspace.entity.typePublication
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