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Dynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applications

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dc.citedby12
dc.contributor.authorSughanthy S.A.P.en_US
dc.contributor.authorAnsari M.N.M.en_US
dc.contributor.authorAtiqah A.en_US
dc.contributor.authorid57205239893en_US
dc.contributor.authorid55489853600en_US
dc.contributor.authorid55366998300en_US
dc.date.accessioned2023-05-29T08:10:55Z
dc.date.available2023-05-29T08:10:55Z
dc.date.issued2020
dc.descriptionBiocompatibility; Biomaterials; Biomechanics; Composite materials; Dichloromethane; Dynamics; Functional polymers; Hydroxyapatite; Morphology; Polyethylene terephthalates; Polyethylenes; Scaffolds (biology); Scanning electron microscopy; Tissue; Tissue engineering; Dynamic mechanical analysis (DMA); Engineering polymers; Nano bio composites; Nanofibrous scaffolds; Polyethylene terephthalates (PET); Synthetic biomaterials; Thermomechanical properties; Tissue engineering applications; Plastic bottlesen_US
dc.description.abstractSynthetic biomaterials are widely used for the treatment of diseased or damaged tissue in the field of tissue engineering. Polyethylene terephthalate (PET) is a synthetic thermoplastic engineering polymer with high commercial and industrial interest and has been widely used as implant material in biomedical engineering. Despite that, PET has limited applications due to its high hydrophobicity. Hydroxyapatite (HA) is one of the known biocompatible ceramic for the development of porous scaffolds for bone replacement and tissue engineering due to its resemblance to the mineral constituents of human bones and teeth. Therefore, HA was functionalized into the PET matrix in order to improve the limitation. In this research, PET-HA nano-biocomposite scaffold was electrospun using the electrospinning system. PET and HA were dissolved using trifluoroacetic acid (TFA) and dichloromethane (DCM). The nanofibrous scaffolds were produced at optimum process parameters. The morphology studies were performed using a Scanning Electron Microscope (SEM) and thermomechanical properties were evaluated using Dynamic Mechanical Analysis (DMA). From the morphology analysis, PET-HA nano-biocomposite scaffold which composed of 96% of PET and 4% of HA, has obtained the largest fiber diameter. The DMA analysis showed that the addition of HA improved mechanical properties. However, PET-HA nano-biocomposite scaffold composed of 98% of PET and 2% of HA was preferred as it has the lower value of storage and loss modulus because the application was focusing on the skin where the more flexible scaffold was needed. The PET-HA nano-biocomposite scaffold fabricated has good potential to be used in tissue engineering applications. � 2019 The Authors.en_US
dc.description.natureFinalen_US
dc.identifier.doi10.1016/j.jmrt.2019.12.066
dc.identifier.epage2356
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85078731187
dc.identifier.spage2350
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85078731187&doi=10.1016%2fj.jmrt.2019.12.066&partnerID=40&md5=230f6f3234471dc12c620e2d376c1141
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/25560
dc.identifier.volume9
dc.publisherElsevier Editora Ltdaen_US
dc.relation.ispartofAll Open Access, Gold
dc.sourceScopus
dc.sourcetitleJournal of Materials Research and Technology
dc.titleDynamic mechanical analysis of polyethylene terephthalate/hydroxyapatite biocomposites for tissue engineering applicationsen_US
dc.typeArticleen_US
dspace.entity.typePublication
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