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New insights of phenolic compounds from optimized fruit extract of Ficus auriculata

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dc.citedby1
dc.contributor.authorShahinuzzaman M.en_US
dc.contributor.authorAkhtar P.en_US
dc.contributor.authorAmin N.en_US
dc.contributor.authorAhmed Y.en_US
dc.contributor.authorAnuar F.H.en_US
dc.contributor.authorMisran H.en_US
dc.contributor.authorAkhtaruzzaman M.en_US
dc.contributor.authorid57193799716en_US
dc.contributor.authorid56419672800en_US
dc.contributor.authorid7102424614en_US
dc.contributor.authorid14832383900en_US
dc.contributor.authorid57216729900en_US
dc.contributor.authorid6506899840en_US
dc.contributor.authorid57195441001en_US
dc.date.accessioned2023-05-29T09:05:26Z
dc.date.available2023-05-29T09:05:26Z
dc.date.issued2021
dc.descriptionantioxidant; phenol derivative; plant extract; solvent; centrifugation; chemistry; Ficus; filtration; fruit; isolation and purification; ultrasound; Antioxidants; Centrifugation; Ficus; Filtration; Fruit; Phenols; Plant Extracts; Solvents; Ultrasonic Wavesen_US
dc.description.abstractIn this study, the extraction conditions extracted maximize amounts of phenolic and bioactive compounds from the fruit extract of Ficus auriculata by using optimized response surface methodology. The antioxidant capacity was evaluated through the assay of radical scavenging ability on DPPH and ABTS as well as reducing power assays on total phenolic content (TPC). For the extraction purpose, the ultrasonic assisted extraction technique was employed. A second-order polynomial model satisfactorily fitted to the experimental findings concerning antioxidant activity (R2 = 0.968, P < 0.0001) and total phenolic content (R2 = 0.961, P < 0.0001), indicating a significant correlation between the experimental and expected value. The highest DPPH radical scavenging activity was achieved 85.20 � 0.96% at the optimum extraction parameters of 52.5% ethanol (v/v), 40.0��C temperature, and 22�min extraction time. Alternatively, the highest yield of total phenolic content was found 31.65 � 0.94�mg GAE/g DF at the optimum extraction conditions. From the LC�ESI�MS profiling of the optimized extract, 18 bioactive compounds were tentatively identified, which may regulate the antioxidant activity of fruits of F. auriculata. � 2021, The Author(s).en_US
dc.description.natureFinalen_US
dc.identifier.ArtNo12503
dc.identifier.doi10.1038/s41598-021-91913-w
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85108007494
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85108007494&doi=10.1038%2fs41598-021-91913-w&partnerID=40&md5=a836b96432b349c7780cecda50858613
dc.identifier.urihttps://irepository.uniten.edu.my/handle/123456789/25889
dc.identifier.volume11
dc.publisherNature Researchen_US
dc.relation.ispartofAll Open Access, Gold, Green
dc.sourceScopus
dc.sourcetitleScientific Reports
dc.titleNew insights of phenolic compounds from optimized fruit extract of Ficus auriculataen_US
dc.typeArticleen_US
dspace.entity.typePublication
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